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TH2 inflammation repressed by chemokines

The proto-oncogene BCL6 participates in the regulation of immune responses; a lack of it leads to generalized type 2 inflammation. Macrophage chemokine genes have now been identified as targets for BCL-6 repression and perhaps induce this inflammation.

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References

  1. Trinchieri, G. Int. Rev. Immunol. 16, 365–96 (1998).

    Article  CAS  PubMed  Google Scholar 

  2. Magram, J. et al. Ann. NY Acad. Sci. 795, 60– 70 (1996).

    Article  CAS  PubMed  Google Scholar 

  3. Mattner, F. et al. Eur. J. Immunol. 26, 1553– 1559 (1996).

    Article  CAS  PubMed  Google Scholar 

  4. Kaplan, M. H., Schindler, U., Smiley, S. T. & Grusby, M. J. Immunity 4, 313–319 ( 1996).

    Article  CAS  PubMed  Google Scholar 

  5. Toney et al. Nature Immunol. 1, 214–220 ( 2000).

    Article  CAS  Google Scholar 

  6. Kerckaert, J. et al. Nature Genet. 5, 66– 70 (1993).

    Article  CAS  PubMed  Google Scholar 

  7. Ye, B., Rao, P., Chaganti, R. & Della-Favera, R. Cancer Res. 53, 2732–2735 ( 1993).

    CAS  PubMed  Google Scholar 

  8. Cattoretti, G. et al. Blood 86, 45–53 (1995).

    CAS  PubMed  Google Scholar 

  9. Yamochi, T. et al. Leukemia 11, 694–700 (1997).

    Article  CAS  PubMed  Google Scholar 

  10. Harris, M. B. et al. Mol. Cell. Biol. 19, 7264– 7275 (1999).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Dent, A. L., Shaffer, A. L., Yu, X., Allman, D. & Staudt, L. M. Science 276, 589– 592 (1997).

    Article  CAS  PubMed  Google Scholar 

  12. Ye, H. B. et al. Nature Genet. 16, 161– 170 (1997).

    Article  CAS  PubMed  Google Scholar 

  13. Dent, A. L., Hu-Li, J., Paul, W. E., and Staudt, L. M. Proc. Natl Acad. Sci. USA 95, 13823–13828 (1998).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Karpus, W. J. et al. J. Immunol. 158, 4129– 4136 (1997).

    CAS  PubMed  Google Scholar 

  15. Gu, L. et al. Nature 404, 407–411 (2000).

    Article  CAS  PubMed  Google Scholar 

  16. Braun, M. C. et al. J. Immunol. 164, 3009– 3017 (2000).

    Article  CAS  PubMed  Google Scholar 

Download references

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Canfield, S., Rothman, P. TH2 inflammation repressed by chemokines. Nat Immunol 1, 189–190 (2000). https://doi.org/10.1038/79720

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