It is becoming more apparent that some B cells do not carry the same antigen receptors throughout their life. B cells that have edited their receptors have now been found in humans as rare cells that accumulate in arthritic joints.
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References
Nemazee, D. A. & Weigert, M. G. J. Exp. Med. 191, 1813–1818 (2000).
Melchers, F. Proc. Natl Acad. Sci., U.S A. 96, 2571– 2573 (1999).
Kline, G. H. et al. J. Immunol. 161, 1608– 1618 (1998).
Han, S., Zheng, B., Schatz, D. G., Spanopoulou, E. & Kelsoe, G. Science 274, 2094– 2097 (1996).
Yu, W. et al. Nature 400, 682–687 (1999).
Meffre, E. et al. Nature Immunology 1, 207– 213 (2000).
Kirkham, P. M. & Schroeder, H. W., Jr Semin. Immunol. 6, 347–360 ( 1994).
Guelpa-Fonlupt, V. et al. Mol. Immunol. 31, 1099– 1108 (1994).
Shiokawa, S. et al. J. Immunol. 162, 6060– 6070 (1999).
Bridges, S.L., Jr. et al. J. Clin. Invest. 96, 831–841 (1995).
Schettino, E. W., Chai, S. K., Kasaian, M. T., Schroeder, H. W., Jr & Casali, P. J. Immunol. 158, 2477–2489 (1997).
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Schroeder, H., Kirkham, P. Marriage, divorce, and promiscuity in human B cells. Nat Immunol 1, 187–188 (2000). https://doi.org/10.1038/79717
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DOI: https://doi.org/10.1038/79717
