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Cat and mouse

New findings show that ERAAP, an endoplasmic reticulum aminopeptidase involved in antigen processing, helps mice survive encounters with a feline-derived parasite.

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Figure 1: Processing and presentation of an immunodominant protective CD8+ T cell epitope from T. gondii requires trimming by ERAAP.

Katie Ris-Vicari

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Delgado, J., Jensen, P. Cat and mouse. Nat Immunol 9, 829–830 (2008). https://doi.org/10.1038/ni0808-829

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