Many aspects of the CD8+ T lymphocyte response are 'programmed' by inductive stimuli during primary activation. A recent Nature paper shows that interleukin 2 signals endow CD8 T cells with the capacity for secondary population expansion during priming.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Kim Caesar
References
Sprent, J. & Surh, C.D. Annu. Rev. Immunol. 20, 551–579 (2002).
Masopust, D., Kaech, S.M., Wherry, E.J. & Ahmed, R. Curr. Opin. Immunol. 16, 217–225 (2004).
Williams, M.A., Tyznik, A.J. & Bevan, M.J. Nature 441, 890–893 (2006).
Boyman, O., Kovar, M., Rubinstein, M.P., Surh, C.D. & Sprent, J. Science 311, 1924–1927 (2006).
Bevan, M.J. Nat. Rev. Immunol. 4, 595–602 (2004).
Bourgeois, C., Rocha, B. & Tanchot, C. Science 297, 2060–2063 (2002).
Janssen, E.M. et al. Nature 421, 852–856 (2003).
Shedlock, D.J. & Shen, H. Science 300, 337–339 (2003).
Sun, J.C. & Bevan, M.J. Science 300, 339–342 (2003).
Sun, J.C., Williams, M.A. & Bevan, M.J. Nat. Immunol. 5, 927–933 (2004).
Granucci, F., Zanoni, I., Feau, S. & Ricciardi-Castagnoli, P. EMBO J. 22, 2546–2551 (2003).
Tham, E.L., Shrikant, P. & Mescher, M.F. J. Immunol. 168, 1190–1197 (2002).
Janssen, E.M. et al. Nature 434, 88–93 (2005).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Schoenberger, S., Janssen, E. IL-2 gets with the program. Nat Immunol 7, 798–800 (2006). https://doi.org/10.1038/ni0806-798
Issue Date:
DOI: https://doi.org/10.1038/ni0806-798
