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Uncovering new complexities in mast cell signaling

Nature Immunology volume 3, pages 707708 (2002) | Download Citation

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FcεRI activation of mast cells was thought to be Lyn-dependent. It now appears that FcεRI also uses a Fyn kinase–dependent pathway that is essential for mast cell degranulation.

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Affiliations

  1. Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. mnadler@caregroup.harvard.edu

    • Monica J.S. Nadler
    •  & Jean-Pierre Kinet

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DOI

https://doi.org/10.1038/ni0802-707

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