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Dendritic cells at the host-pathogen interface

Nature Immunology volume 3, pages 699–702 (2002)Cite this article

A May 2002 workshop in Virginia, USA, focused on dendritic cells. Kelsall and colleagues summarize here some of the outstanding questions raised at the conference.

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Figure 1: The complexity of pathogen-DC interactions.

References

  1. Henri, S. et al. J. Immunol. 167, 741–748 (2001).

    Article  CAS  Google Scholar 

  2. Iwasaki, A. & Kelsall, B.L. J. Immunol. 166, 4884–4890 (2001).

    Article  CAS  Google Scholar 

  3. Shortman, K. & Liu, Y.J. Nature Rev. Immunol. 2, 151–161 (2002).

    Article  CAS  Google Scholar 

  4. Maldonado-Lopez, R. et al. J. Exp. Med. 189, 587–592 (1999).

    Article  CAS  Google Scholar 

  5. Pulendran, B. et al. Proc. Natl. Acad. Sci. USA 96, 1036–1041 (1999).

    Article  CAS  Google Scholar 

  6. Underhill, D.M. et al. Nature 401, 811–815 (1999).

    Article  CAS  Google Scholar 

  7. Wagner, H. Curr. Opin, Microbiol. 5, 62–69 (2002).

    Article  CAS  Google Scholar 

  8. Akira, S., Takeda, K. & Kaisho, T. Nature Immunol. 2, 675–680 (2001).

    Article  CAS  Google Scholar 

  9. Kaisho, T. & Akira, S. Trends Immunol. 22, 78–83 (2001).

    Article  CAS  Google Scholar 

  10. Pulendran, B. et al. J. Immunol. 167, 5067–5076 (2001).

    Article  CAS  Google Scholar 

  11. Gagliardi, M.C. et al. Eur. J. Immunol. 30, 2394–2403 (2000).

    Article  CAS  Google Scholar 

  12. Braun, M.C., He, J., Wu, C.Y. & Kelsall, B.L. J. Exp. Med. 189, 541–552 (1999).

    Article  CAS  Google Scholar 

  13. Kalinski, P., Hilkens, C.M., Wierenga, E.A. & Kapsenberg, M.L. Immunol. Today 20, 561–567 (1999).

    Article  CAS  Google Scholar 

  14. de Jong, E.C. et al. J. Immunol. 168, 1704–1709 (2002).

    Article  CAS  Google Scholar 

  15. Siegal, F.P. et al. Science 284, 1835–1837 (1999).

    Article  CAS  Google Scholar 

  16. Asselin-Paturel, C. et al. Nature Immunol. 2, 1144–1150 (2001).

    Article  CAS  Google Scholar 

  17. Nakano, H., Yanagita, M. & Gunn, M.D. J. Exp. Med. 194, 1171–1178 (2001).

    Article  CAS  Google Scholar 

  18. Bjorck, P. Blood 98, 3520–3526 (2001).

    Article  CAS  Google Scholar 

  19. Kadowaki, N. et al. J. Exp. Med. 194, 863–869 (2001).

    Article  CAS  Google Scholar 

  20. Krug, A. et al. Eur. J. Immunol. 31, 3026–3037 (2001).

    Article  CAS  Google Scholar 

  21. Barchet, W. et al. J. Exp. Med. 195, 507–516 (2002).

    Article  CAS  Google Scholar 

  22. Dalod, M. et al. J. Exp. Med. 195, 517–528 (2002).

    Article  CAS  Google Scholar 

  23. Kadowaki, N., Antonenko, S., Lau, J.Y. & Liu, Y.J. J. Exp. Med. 192, 219–226 (2000).

    Article  CAS  Google Scholar 

  24. Langenkamp, A., Messi, M., Lanzavecchia, A. & Sallusto, F. Nature Immunol. 1, 311–316 (2000).

    Article  CAS  Google Scholar 

  25. Gilliet, M. & Liu, Y.J. J. Exp. Med. 195, 695–704 (2002).

    Article  CAS  Google Scholar 

  26. Henderson, R.A., Watkins, S.C. & Flynn, J.L. J. Immunol. 159, 635 (1997).

  27. Fortsch, D., Rollinghoff, M. & Stenger, S. J. Immunol. 165, 978–987 (2000).

    Article  CAS  Google Scholar 

  28. Vidalain, P.O., Azocar, O., Rabourdin-Combe, C. & Servet-Delprat, C. Immunobiology. 204, 629–638 (2001).

    Article  CAS  Google Scholar 

  29. Urban, B.C., Willcox, N. & Roberts, D.J. Proc. Natl. Acad. Sci. USA 98, 8750–8755 (2001).

    Article  CAS  Google Scholar 

  30. Geijtenbeek, T.B. et al. Cell 100, 587–597 (2000).

    Article  CAS  Google Scholar 

  31. Kwon, D.S., Gregorio, G., Bitton, N., Hendrickson, W.A. & Littman, D.R. Immunity 16, 135–144 (2002).

    Article  CAS  Google Scholar 

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Acknowledgements

We thank R. Germain for his contribution to the content of this Commentary, A. Sher and C. Reise e Sousa for their comments on the manuscript, and all the participants of this conference, many of whom's outstanding work could not be included here.

Author information

Authors and Affiliations

  1. Laboratory of Clinical Investigation, NIAID, NIH, Bethesda, MD, USA

    Brian L. Kelsall

  2. Department of Molecular Microbiology and Immunology, Brown University, Providence, RI, USA

    Christine A. Biron

  3. Division of AIDS, NIAID, NIH, Bethesda, MD, USA

    Opendra Sharma

  4. Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK

    Paul M. Kaye

Authors
  1. Brian L. Kelsall
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  2. Christine A. Biron
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  3. Opendra Sharma
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  4. Paul M. Kaye
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Correspondence to Brian L. Kelsall.

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Kelsall, B., Biron, C., Sharma, O. et al. Dendritic cells at the host-pathogen interface. Nat Immunol 3, 699–702 (2002). https://doi.org/10.1038/ni0802-699

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