The anti-influenza CD8+ T cell response in HLA-A2 adults is dominated by a specific TCR. The crystal structure of the TCR and peptide-MHC complex show unusual interactions that help to explain the molecular basis of this dominant TCR selection.
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Davis, M. The problem of plain vanilla peptides. Nat Immunol 4, 649–650 (2003). https://doi.org/10.1038/ni0703-649
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DOI: https://doi.org/10.1038/ni0703-649
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