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To B or not to B: TNF family signaling in lymphocytes

BLyS and family are known to affect B cells in a positive fashion. Knock-outs of BLyS receptors indicate some new functions, including negative regulation by one BLyS receptor, TACI.

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Siegel, R., Lenardo, M. To B or not to B: TNF family signaling in lymphocytes. Nat Immunol 2, 577–578 (2001). https://doi.org/10.1038/89715

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