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Trimming the fat: a Brucella abortus survival strategy

Some microbes can circumvent phagocytosis by interfering with membrane transport systems. Brucella do this by making cyclic glucan molecules that interfere with lipid raft–mediated vacuole maturation.

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Figure 1: A potential function for lipid rafts as signaling platforms important for phagosome maturation.

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Roy, C. Trimming the fat: a Brucella abortus survival strategy. Nat Immunol 6, 546–548 (2005). https://doi.org/10.1038/ni0605-546

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