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Trawling for treasure: tales of T-bet

Nature Immunology volume 8, pages 448450 (2007) | Download Citation

Discovering the transcription factors that direct lineage commitment in the T helper cell was a formidable task. Laurie Glimcher describes how she and Susanne Szabo hunted down T-bet, a transcription factor that is a 'master regulator' of commitment to the T helper type 1 lineage.

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Acknowledgements

I thank the graduate students and postdoctoral fellows I have worked with over the past two decades and the US National Institutes of Health for its continued support since 1982.

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Affiliations

  1. Laurie H. Glimcher is in the Department of Immunology and Infectious Diseases, Harvard School of Public Health, and the Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA. lglimche@hsph.harvard.edu

    • Laurie H Glimcher

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The author declares no competing financial interests.

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https://doi.org/10.1038/ni0507-448

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