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T cells join the Blimp-1 brigade

B lymphocyte–induced maturation protein 1 (Blimp-1) is known as a 'master regulator' of plasma cell differentiation. New findings suggest that the influence of this transcription factor extends beyond the B cell lineage.

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Figure 1: Blimp-1 is a transcriptional repressor whose realm of activity has been extended beyond that of a 'master regulator' of B cell differentiation to include regulation of T cell homeostasis and activation.

Katie Ris

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Fink, P. T cells join the Blimp-1 brigade. Nat Immunol 7, 445–446 (2006). https://doi.org/10.1038/ni0506-445

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