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Contact hypersensitivity: not just T cells!

Contact hypersensitivity is a form of delayed-type hypersensitivity, a classic T cell–mediated, clinically important phenomenon. Unexpectedly, a new study indicates that natural killer cells may mediate contact hypersensitivity and demonstrate adaptive, memory-like activity.

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Figure 1: Key evidence supporting involvement of NK cells in CHS.

Katie Ris

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Yokoyama, W. Contact hypersensitivity: not just T cells!. Nat Immunol 7, 437–439 (2006). https://doi.org/10.1038/ni0506-437

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