Historical insight: Immunology's founding fathers argued fiercely about whether Metchnikoff's phagocytes or Ehrlich's antibodies were the most important mediators of immunity. Antibodies won out, but even after lymphocytes re-established cellular immunology, the humoralist-cellularist divide persisted.
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Silverstein, A. Cellular versus humoral immunology: a century-long dispute. Nat Immunol 4, 425–428 (2003). https://doi.org/10.1038/ni0503-425
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DOI: https://doi.org/10.1038/ni0503-425
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