CD1 presents lipid antigens to T cells. Intrinsic properties of microbial lipids, such as alkyl chain length, may be essential determinants of their efficient presentation to T cells.
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Bendelac, A., Teyton, L. & Savage, P. Lipid presentation by CD1: the short and the long lipid story. Nat Immunol 3, 421–422 (2002). https://doi.org/10.1038/ni0502-421
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DOI: https://doi.org/10.1038/ni0502-421