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Neuropilin-1: another neuronal molecule in the “immunological synapse”

Nature Immunology volume 3, pages 418–419 (2002)Cite this article

Synapse formation in the immune system and the nervous system have common features. The identification of neuropilin-1, a neuronal receptor, as participating in naïve T cell–DC contact helps emphasize the molecular similarities between these systems.

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Figure 1: Complexities in the interaction of naïve T cells with DCs.

Bob Crimi

References

  1. Tordjman, R. et al. Nature Immunol. 3, 477–482 (2002).

    Article  CAS  Google Scholar 

  2. Wülfing, C., Sjaastad, M. D. & Davis, M. M. Proc. Natl. Acad. Sci. USA 95, 6302–6307 (1998).

    Article  Google Scholar 

  3. Bunnell, S. C., Kapoor, V., Trible, R. P., Zhang, W. & Samelson, L. E. Immunity 14, 315–329 (2001).

    Article  CAS  Google Scholar 

  4. Lowin-Kropf, B., Shapiro, V. S. & Weiss, A. J. Cell Biol. 140, 861–871 (1998).

    Article  CAS  Google Scholar 

  5. Croft, M. & Dubey, C. Crit. Rev. Immunol. 17, 89–118 (1997).

    Article  CAS  Google Scholar 

  6. Monks, C. R., Freiberg, B. A., Kupfer, H., Sciaky, N. & Kupfer, A. Nature 395, 82–86 (1998).

    Article  CAS  Google Scholar 

  7. Scheiffele, P., Fan, J., Choih, J., Fetter, R. & Serafini, T. Cell 101, 657–669 (2000).

    Article  CAS  Google Scholar 

  8. Khan, A. A., Bose, C., Yam, L. S., Soloski, M. J. & Rupp, F. Science 292, 1681–1686 (2001).

    Article  CAS  Google Scholar 

  9. Revy, P., Sospedra, M., Barbour, B. & Trautmann, A. Nature Immunol. 2, 925–931 (2001).

    Article  CAS  Google Scholar 

  10. Geijtenbeek, T. B. et al. Cell 100, 575–585 (2000).

    Article  CAS  Google Scholar 

  11. Al-Alwan, M. M., Rowden, G., Lee, T. D. & West, K. A. J. Immunol. 166, 1452–1456 (2001).

    Article  CAS  Google Scholar 

  12. Liu, B. P. & Strittmatter, S. M. Curr. Opin. Cell Biol. 13, 619–626 (2001).

    Article  CAS  Google Scholar 

  13. Singer, S. J. Science 255, 1671–1677 (1992).

    Article  CAS  Google Scholar 

  14. Chang, S. & De Camilli, P. Nature Neurosci. 4, 787–793 (2001).

    Article  CAS  Google Scholar 

  15. Wong, W. T. & Wong, R. O. Nature Neurosci. 4, 351–352 (2001).

    Article  CAS  Google Scholar 

  16. Ziv, N. E. & Smith, S. J. Neuron 17, 91–102 (1996).

    Article  CAS  Google Scholar 

  17. Sheng, M. & Sala, C. Annu. Rev. Neurosci. 24, 1–29 (2001).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Center for Immunology and Department of Cell Biology, UT Southwestern Medical Center, Dallas, 75390-9093, TX, USA

    Christoph Wülfing

  2. Hyseq Inc., Sunnyvale, 94085, CA, USA

    Fabio Rupp

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  1. Christoph Wülfing
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  2. Fabio Rupp
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Wülfing, C., Rupp, F. Neuropilin-1: another neuronal molecule in the “immunological synapse”. Nat Immunol 3, 418–419 (2002). https://doi.org/10.1038/ni0502-418

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