To kill, you have to duck an HDAC

Analysis of the serine-threonine phosphoproteome leads to the intriguing find that phosphorylation of the histone deacetylase HDAC7 is key to cytotoxic T lymphocyte function.

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Figure 1: Regulation of the localization and function of HDAC7 by the TCR.

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Correspondence to Amnon Altman.

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Altman, A., Kong, K. To kill, you have to duck an HDAC. Nat Immunol 12, 279–281 (2011). https://doi.org/10.1038/ni0411-279

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