How immunoglobulin gene loci are specifically targeted by activation-induced cytidine deaminase while the rest of the genome avoids potentially mutagenic events is becoming clearer.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Chaudhuri, J., Khuong, C. & Alt, F.W. Nature 430, 992–998 (2004).
Chaudhuri, J. et al. Nature 422, 726–730 (2003).
Liu, M. et al. Nature 451, 841–845 (2008).
Vuong, et al. Nat. Immunol. 10, 420–426 (2009).
Teng, G. et al. Immunity 28, 621–629 (2008).
de Yébenes, V.G. et al. J. Exp. Med. 205, 2199–2206 (2008).
Aoufouchi, S. et al. J. Exp. Med. 205, 1357–1368 (2008).
Sernández, I.V., de Yébenes, V.G., Dorsett, Y. & Ramiro, A.R. PLoS ONE 3, e3927 (2008).
Basu, U. et al. Nature 438, 508–511 (2005).
Cheng, H.L. et al. Proc. Natl. Acad. Sci. USA 106, 2717–2722 (2009).
Pasqualucci, L., Kitaura, Y., Gu, H. & Dalla-Favera, R. Proc. Natl. Acad. Sci. USA 103, 395–400 (2006).
Basu, U., Wang, Y. & Alt, F.W. Mol. Cell 32, 285–291 (2008).
Manis, J.P. et al. Nat. Immunol. 5, 481–487 (2004).
Reina-San-Martin, B. et al. J. Exp. Med. 197, 1767–1778 (2003).
Min, I.M. et al. Immunity 19, 515–524 (2003).
Francis, S.H. & Corbin, J.D. Annu. Rev. Physiol. 56, 237–272 (1994).
Fanning, E., Klimovich, V. & Nager, A.R. Nucleic Acids Res. 34, 4126–4137 (2006).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rada, C. AID and RPA: PKA makes the connection local. Nat Immunol 10, 367–369 (2009). https://doi.org/10.1038/ni0409-367
Issue Date:
DOI: https://doi.org/10.1038/ni0409-367
