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New niches for B cells

The bone marrow contains specialized microenvironments that maintain blood cells and supply the requisite factors for their development. Newly identified bone marrow–resident dendritic cells create unique niches for mature B cells.

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Figure 1: Proposed localization of mature B cells and their niches.

Kim Caesar

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Nagasawa, T. New niches for B cells. Nat Immunol 9, 345–346 (2008). https://doi.org/10.1038/ni0408-345

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