News & Views | Published:

Type 1 diabetes: virus infection or autoimmune disease?

Nature Immunology volume 3, pages 338340 (2002) | Download Citation

Subjects

What does Coxsackie virus have to do with diabetes? Evidence is emerging that insulin-producing β cells are highly susceptible to acute infection by Coxsackie virus if their production of interferon is inhibited, resulting in diabetes.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    et al. Nature Immunol. 2, 375–384 (2002).

  2. 2.

    et al. Diabetologia 36, 687–695 (1993).

  3. 3.

    Curr. Top. Micro. Immunol. 164, 95–123 (1990).

  4. 4.

    , & J. Gen. Virol. 81, 2341–2364 (2000).

  5. 5.

    et al. Nature Med. 6, 693–697 (2000).

  6. 6.

    et al. Nature Med. 7, 781–785 (1998).

  7. 7.

    & Cell. Mol. Life Sci. 57, 542–551 (2000).

  8. 8.

    & Nature Immunol. 2, 797–801 (2001).

  9. 9.

    , & Science 272, 1947–1950 (1996).

  10. 10.

    et al. Immunity 15, 591–601 (2001).

  11. 11.

    & Annu. Rev. Immunol. 19, 65–91 (2001).

  12. 12.

    & Immunol. Today 14, 426–430 (1993).

  13. 13.

    et al. J. Autoimm. 16, 175–186 (2001).

  14. 14.

    & Nature Immunol. 2, 767–768 (2001).

Download references

Author information

Affiliations

  1. Departments of Pathology and of Molecular Microbiology & Immunology, Johns Hopkins Medical Institutions, Baltimore, MD 21205 USA. nrrose@jhsph.edu

    • DeLisa Fairweather
    •  & Noel R. Rose

Authors

  1. Search for DeLisa Fairweather in:

  2. Search for Noel R. Rose in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/ni0402-338

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing