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Finally, MALT1 is a protease!

Two groups demonstrate proteolytic activity for MALT1, a component of the signaling pathway mediating antigen receptor–dependent stimulation of the transcription factor NF-κB, and identify its first substrates.

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Figure 1: The MALT1 caspase-like domain has proteolytic activity.

Katie Ris-Vicari

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McAllister-Lucas, L., Lucas, P. Finally, MALT1 is a protease!. Nat Immunol 9, 231–233 (2008). https://doi.org/10.1038/ni0308-231

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