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HIV's gut feeling

Human immunodeficiency virus may direct its assault on gut-associated CD4+ T cells by means of the gut-homing integrin α4β7.

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Figure 1: A model for an α4β7-mediated increase in the efficiency of HIV-1 spread in GALT.

Katie Ris-Vicari


  1. Haase, A.T. Nat. Rev. Immunol. 5, 783–792 (2005).

    Article  CAS  Google Scholar 

  2. Picker, L.J. Curr. Opin. Immunol. 18, 399–405 (2006).

    Article  CAS  Google Scholar 

  3. Brenchley, J.M. et al. Nat. Med. 12, 1365–1371 (2006).

    Article  CAS  Google Scholar 

  4. Arthos, J. et al. Nat. Immunol. 9, 301–309 (2008).

    Article  CAS  Google Scholar 

  5. Johansson-Lindbom, B. & Agace, W.W. Immunol. Rev. 215, 226–242 (2007).

    Article  CAS  Google Scholar 

  6. Lederman, M.M. et al. J. Am. Med. Assoc. 296, 815–826 (2006).

    Article  CAS  Google Scholar 

  7. Harouse, J.M. et al. Science 284, 816–819 (1999).

    Article  CAS  Google Scholar 

  8. Rose, D.M., Alon, R. & Ginsberg, M.H. Immunol. Rev. 218, 126–134 (2007).

    Article  CAS  Google Scholar 

  9. Tardif, M.R. & Tremblay, M.J. J. Virol. 79, 13714–13724 (2005).

    Article  CAS  Google Scholar 

  10. Jolly, C., Mitar, I. & Sattentau, Q.J. J. Virol. 81, 13916–13921 (2007)

    Article  CAS  Google Scholar 

  11. Piguet, V. & Sattentau, Q. J. Clin. Invest. 114, 605–610 (2004).

    Article  CAS  Google Scholar 

  12. Tardif, M.R. & Tremblay, M.J. J. Immunol. 175, 926–935 (2005).

    Article  CAS  Google Scholar 

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Sattentau, Q. HIV's gut feeling. Nat Immunol 9, 225–227 (2008).

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