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Treg cells: guardians for life

Regulatory T cells expressing the transcription factor Foxp3 are known to control autoreactivity during and subsequent to the development of the peripheral immune system. New evidence emphasizes the fact that those cells are constant and powerful guardians against the state of 'horror autotoxicus'.

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Figure 1: Treg cells control lympho-myeloid cell proliferation in adults.

Katie Ris

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Hill, J., Benoist, C. & Mathis, D. Treg cells: guardians for life. Nat Immunol 8, 124–125 (2007). https://doi.org/10.1038/ni0207-124

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