Tolerance to self is engendered by multiple mechanisms. Lymph node stromal cells are now found to contribute to self-tolerance by their endogenous expression of peripheral tissue antigens.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Katie Ris
References
Hogquist, K.A., Baldwin, T.A. & Jameson, S.C. Nat. Rev. Immunol. 5, 772–782 (2005).
Redmond, W.L. & Sherman, L.A. Immunity 22, 275–284 (2005).
Lee, J. et al. Nat. Immunol. 8, 181–190 (2007).
Kyewski, B. & Klein, L. Annu. Rev. Immunol. 24, 571–606 (2006).
Anderson, M.S. et al. Science 298, 1395–1401 (2002).
Heath, W.R. & Carbone, F.R. Annu. Rev. Immunol. 19, 47–64 (2001).
Vezys, V., Olson, S. & Lefrancois, L. Immunity 12, 505–514 (2000).
Bonasio, R. et al. Nat. Immunol. 7, 1092–1100 (2006).
Gallegos, A.M. & Bevan, M.J. J. Exp. Med. 200, 1039–1049 (2004).
Bajenoff, M. et al. 25, 989–1001 (2006).
Klein, L., Klugmann, M., Nave, K.A., Tuohy, V.K. & Kyewski, B. Nat. Med. 6, 56–61 (2000).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Zehn, D., Bevan, M. More promiscuity resulting in more tolerance. Nat Immunol 8, 120–122 (2007). https://doi.org/10.1038/ni0207-120
Issue Date:
DOI: https://doi.org/10.1038/ni0207-120
