Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Presenting fats with SAPs

CD1 presents lipids to unique subsets of T cells, but how are these lipids loaded onto CD1? A series of three papers has shed light on the molecules that facilitate this process.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Five steps in the traffic and antigen loading of human CD1b and mouse CD1d molecules.

C.C.

References

  1. Zhou, D. et al. Science (22 December 2003) doi: 10.1126/science.1092009.

  2. Kang, S.-J. & Cresswell, P. Nat. Immunol. 5, 175–181 (2004).

    Article  CAS  Google Scholar 

  3. Winau, F. et al. Nat. Immunol. 5, 161–174 (2004).

    Google Scholar 

  4. Vincent, M.S., Gumperz, J.E. & Brenner, M.B. Nat. Immunol. 4, 517–523 (2003).

    Article  CAS  Google Scholar 

  5. Moody, D.B. & Porcelli, S.A. Nat. Rev. Immunol. 3, 11–22 (2003).

    Article  CAS  Google Scholar 

  6. Prigozy, T.I. et al. Science 291, 664–667 (2001).

    Article  CAS  Google Scholar 

  7. Jayawardena-Wolf, J., Benlagha, K., Chiu, Y.H., Mehr, R. & Bendelac, A. Immunity 15, 897–908 (2001).

    Article  CAS  Google Scholar 

  8. Briken, V., Jackman, R.M., Dasgupta, S., Hoening, S. & Porcelli, S.A. EMBO J. 21, 825–834 (2002).

    Article  CAS  Google Scholar 

  9. Sugita, M. et al. Immunity 16, 697–706 (2002).

    Article  CAS  Google Scholar 

  10. Elewaut, D. et al. J. Exp. Med. 198, 1133–1146 (2003).

    Article  CAS  Google Scholar 

  11. Cernadas, M. et al. J. Immunol. 171, 4149–4155 (2003).

    Article  CAS  Google Scholar 

  12. Schuette, C.G., Pierstorff, B., Huettler, S. & Sandhoff, K. Glycobiology 11, 81R–90R (2001).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kronenberg, M. Presenting fats with SAPs. Nat Immunol 5, 126–127 (2004). https://doi.org/10.1038/ni0204-126

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ni0204-126

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing