Graft-versus-host disease results when donor T cells attack immunocompromised hosts. New data show the distinct environment of Peyer's patches triggers the activation of these aggressive anti-host responses.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Korngold, R. & Sprent, J. J. Exp. Med. 148, 1687–1698 (1978).
Murai, M. et al. Nat. Immunol. 4, 154–160 (2003).
Shlomchik, W.D. et al. Science 285, 412–415 (1999).
Teshima, T. et al. Nat. Med. 8, 575–581 (2002).
Korngold, R. & Sprent, J. Murine models for graft-versus-host disease. In Hematopoietic Cell Transplantation (eds. Thomas, E.D., Blume, K.G. & Forman, S.J.) 296–304 (Blackwell Science, Inc., Boston, 1999).
Neutra, M.R., Mantis, N.J. & Kraehenbuhl, J.P. Nat. Immunol. 2, 1004–1009 (2001).
Nestel, F.P., Price, K.S., Seemayer, T.A. & Lapp, W.S. J. Exp. Med. 175, 405–413 (1992).
Hill, G. & Ferrara, J. Blood 95, 2754–2759 (2000).
Cooke, K. et al. J. Clin. Invest. 7, 1581–1589 (2001).
Panoskaltsis-Mortari, A., Lacey, D.L., Vallera, D.A. & Blazer, B.R. Blood 92, 3960–3967 (1998).
Reddy, P. et al. J. Exp. Med. 194, 1433–1440 (2001).
Ruggeri, L. et al. Science 295, 2097–2100 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ferrara, J. Location, location, location. Nat Immunol 4, 103–104 (2003). https://doi.org/10.1038/ni0203-103
Issue Date:
DOI: https://doi.org/10.1038/ni0203-103