ZAPS electrifies RIG-I signaling

ZAPS, a member of the poly(ADP-ribose) polymerase family, modulates innate antiviral immunity by boosting signaling of the RNA helicase RIG-I.

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Figure 1: Model of the regulation of RIG-I antiviral activity and the innate immune response by ZAPS.


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Correspondence to Michael Gale Jr.

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Liu, H., Gale, M. ZAPS electrifies RIG-I signaling. Nat Immunol 12, 11–12 (2011).

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