ADAR1 catalyzes the deamination of adenosine to inosine in double-stranded RNA. This RNA-editing enzyme is now shown to be involved in hematopoiesis, where it acts to suppress interferon signaling and to block premature apoptosis.
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Iizasa, H., Nishikura, K. A new function for the RNA-editing enzyme ADAR1. Nat Immunol 10, 16–18 (2009). https://doi.org/10.1038/ni0109-16
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DOI: https://doi.org/10.1038/ni0109-16
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