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Lymphoid organogenesis: getting the green light from RORγt

Nature Immunologyvolume 5pages1214 (2004) | Download Citation

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Lymphoid tissue inducer (LTi) cells are central to the development of lymphoid organs during embryonic development. Only these cells express the nuclear receptor RORγt, which turns out to be indispensable for LTi cell survival and function.

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References

  1. 1

    Eberl, G. et al. Nat. Immunol. 3, 64–73 (2003).

  2. 2

    Mebius, R.E. et al. Immunity 7, 493–504 (1997).

  3. 3

    Yoshida, H. et al. J. Immunol. 167, 2511–2521 (2001).

  4. 4

    Mebius, R.E. et al. J. Immunol. 166, 6593–6601 (2001).

  5. 5

    Sun, Z. et al. Science 288, 2369–2373 (2000).

  6. 6

    Kurebayashi, S. et al. Proc. Natl. Acad. Sci. USA 97, 10132–10137 (2000).

  7. 7

    Yokota, Y. et al. Nature 397, 702–706 (1999).

  8. 8

    Stehlin-Gaon, C. et al. Nat. Struct. Biol. 10, 820–825 (2003).

  9. 9

    He, Y.W. et al. Immunity 9, 797–806 (1998).

  10. 10

    Guo, J. et al. Nat. Immunol. 3, 469–476 (2002).

  11. 11

    Müller, G. et al. Immunol. Rev. 195, 117–135 (2003).

  12. 12

    Fu, Y.X. & Chaplin, D.D. Annu. Rev. Immunol. 17, 399–433 (1999).

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Affiliations

  1. Department of Molecular Tumor Genetics and Immunogenetics, Max-Delbrueck-Center for Molecular Medicine, MDC, Robert-Roessle-Strasse 10, Berlin, 13092, Germany

    • Martin Lipp
    •  & Gerd Müller

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https://doi.org/10.1038/ni0104-12

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