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Novel interferons

Type I IFNs are important in antiviral immunity. Two studies report the identification of another family of molecules that have similar properties to the type I IFNs but are otherwise structurally and genetically distinct.

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Figure 1: Comparison of signaling pathways activated by IFN-αβ, IFN-γ and the newly described IFN-λ.

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Vilcek, J. Novel interferons. Nat Immunol 4, 8–9 (2003).

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