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Checks and balances on developing B cells

Nature Immunologyvolume 4pages1315 (2003) | Download Citation

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Signals through the pre-BCR play key roles in B cell development. New data reveal how two downstream components, SLP-65 and the tyrosine kinase Abl, regulate pre-BCR surface expression and immunoglobulin light chain expression.

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Affiliations

  1. Department of Molecular Genetics, Institute for Liver Research, Kansai Medical University, and Laboratory for Lymphocyte Differentiation, RIKEN Research Center for Allergy and Immunology, Moriguchi, 570-8506, Japan

    • Tomohiro Kurosaki

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https://doi.org/10.1038/ni0103-13

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