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(T)Betting on innate lymphoid cells in CNS inflammatory disease

T-bet+NKp46+ subsets of group 1 and group 3 innate lymphoid cells within the meninges initiate neuroinflammation in central nervous system (CNS)-demyelinating disease by regulating both the stability of pathogenic T-bet+ T cells and their access to the CNS.

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Figure 1: Meningeal T-bet+NKp46+ ILCs regulate CNS inflammation.

Kim Caesar/Springer Nature

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Correspondence to Melissa A Brown.

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Brown, M., Russi, A. (T)Betting on innate lymphoid cells in CNS inflammatory disease. Nat Immunol 18, 1063–1064 (2017). https://doi.org/10.1038/ni.3839

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