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Biomarkers of chronic inflammation in disease development and prevention: challenges and opportunities

The US National Institutes of Health convened a workshop on disease-promoting chronic inflammation to identify the challenges and needs in the development of clinically feasible strategies for monitoring a person's inflammation status before, during and after disease occurrence.

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Figure 1: CI is associated with low-grade, persistent physiological responses that can lead to tissue degeneration and a variety of diseases.

Debbie Maizels/Springer Nature


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We thank the workshop speakers for participating and for providing insight in addressing the challenges associated with biomarker identification and leveraging and developing imaging and sensing technologies, as well as strategies for data integration during chronic inflammatory conditions, and for their time and input in reviewing the manuscript. Workshop organizing committee: Natalie Abram, Danielle Carrick, Paige Green, Richard Mazurchuk, Sudhir Srivastava, Piotr Grodzinski, Grace Shen, Julia Berzhanskaya, Antonello Punturieri, Andrei Kindzelski, Barbara Radziszewska, Felipe Sierra, Ronald Kohanski, Miroslaw Mackiewicz, Francesca Macchiarini, Mercy PrabhuDas, Merriline Vedamony, Preethi Chander, Michelle Hamlet and Johanna Dwyer.

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Correspondence to Christina H Liu.

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The authors declare no competing financial interests.

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Liu, C., Abrams, N., Carrick, D. et al. Biomarkers of chronic inflammation in disease development and prevention: challenges and opportunities. Nat Immunol 18, 1175–1180 (2017).

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