The US National Institutes of Health convened a workshop on disease-promoting chronic inflammation to identify the challenges and needs in the development of clinically feasible strategies for monitoring a person's inflammation status before, during and after disease occurrence.
Subscribe to Journal
Get full journal access for 1 year
only $18.75 per issue
All prices are NET prices.
VAT will be added later in the checkout.
Rent or Buy article
Get time limited or full article access on ReadCube.
All prices are NET prices.
Ashley, N.T., Weil, Z.M. & Nelson, R. Annu. Rev. Ecol. Evol. Syst. 43, 385–406 (2012).
Goldberg, E.L. & Dixit, V.D. Immunol. Rev. 265, 63–74 (2015).
Wiley, C.D. & Campisi, J. Cell Metab. 23, 1013–1021 (2016).
Dzutsev, A. et al. Annu. Rev. Immunol. 35, 199–228 (2017).
Kannan, S. et al. Sci. Transl. Med. 4, 130ra146 (2012).
Lamont, R.J. & Hajishengallis, G. Trends Mol. Med. 21, 172–183 (2015).
Martins, M.D. et al. J. Dent. Res. 95, 215–222 (2016).
Morrison, L. et al. BMC Cancer 16, 80 (2016).
Varadhan, R. et al. J. Gerontol. A Biol. Sci. Med. Sci. 69, 165–173 (2014).
Roy, N.S., Wei, Y., Kuklinski, E. & Asbell, P.A. Invest. Ophthalmol. Vis. Sci. 58, BIO1–BIO19 (2017).
Tracy, R.P. et al. J. Am. Heart Assoc. 2, e000117 (2013).
Kreisl, W.C. et al. Neurobiol. Aging 44, 53–61 (2016).
Shin, S.H., Kadayakkara, D.K. & Bulte, J.W. Radiology 282, 194–201 (2017).
Wang, L.V. & Yao, J. Nat. Methods 13, 627–638 (2016).
Abram, T.J. et al. Oral Oncol. 60, 103–111 (2016).
Nakagawa, S. et al. Cancer Cell 30, 879–890 (2016).
Zierer, J. et al. Sci. Rep. 6, 37646 (2016).
Newman, A.B. et al. Int. J. Epidemiol. 45, 1135–1145 (2016).
Zhen, Y., Chu, C., Zhou, S., Qi, M. & Shu, R. Mol. Med. Rep. 12, 5239–5245 (2015).
Hasturk, H. et al. Arterioscler. Thromb. Vasc. Biol. 35, 1123–1133 (2015).
We thank the workshop speakers for participating and for providing insight in addressing the challenges associated with biomarker identification and leveraging and developing imaging and sensing technologies, as well as strategies for data integration during chronic inflammatory conditions, and for their time and input in reviewing the manuscript. Workshop organizing committee: Natalie Abram, Danielle Carrick, Paige Green, Richard Mazurchuk, Sudhir Srivastava, Piotr Grodzinski, Grace Shen, Julia Berzhanskaya, Antonello Punturieri, Andrei Kindzelski, Barbara Radziszewska, Felipe Sierra, Ronald Kohanski, Miroslaw Mackiewicz, Francesca Macchiarini, Mercy PrabhuDas, Merriline Vedamony, Preethi Chander, Michelle Hamlet and Johanna Dwyer.
The authors declare no competing financial interests.
About this article
Cite this article
Liu, C., Abrams, N., Carrick, D. et al. Biomarkers of chronic inflammation in disease development and prevention: challenges and opportunities. Nat Immunol 18, 1175–1180 (2017). https://doi.org/10.1038/ni.3828
Multi-omics: Differential expression of IFN-γ results in distinctive mechanistic features linking chronic inflammation, gut dysbiosis, and autoimmune diseases
Journal of Autoimmunity (2020)
Insufficient efferocytosis by M2-like macrophages as a possible mechanism of neuropathic pain induced by nerve injury
Biochemical and Biophysical Research Communications (2020)
Self‐criticism, interpersonal conditions, and biosystemic inflammation in suicidal thoughts and behaviors within mood disorders: A bio‐cognitive‐interpersonal hypothesis
Journal of Personality (2020)
Nanoscale Horizons (2020)