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Biomarkers of chronic inflammation in disease development and prevention: challenges and opportunities

Nature Immunology volume 18, pages 1175–1180 (2017)Cite this article

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The US National Institutes of Health convened a workshop on disease-promoting chronic inflammation to identify the challenges and needs in the development of clinically feasible strategies for monitoring a person's inflammation status before, during and after disease occurrence.

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Figure 1: CI is associated with low-grade, persistent physiological responses that can lead to tissue degeneration and a variety of diseases.

Debbie Maizels/Springer Nature

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Acknowledgements

We thank the workshop speakers for participating and for providing insight in addressing the challenges associated with biomarker identification and leveraging and developing imaging and sensing technologies, as well as strategies for data integration during chronic inflammatory conditions, and for their time and input in reviewing the manuscript. Workshop organizing committee: Natalie Abram, Danielle Carrick, Paige Green, Richard Mazurchuk, Sudhir Srivastava, Piotr Grodzinski, Grace Shen, Julia Berzhanskaya, Antonello Punturieri, Andrei Kindzelski, Barbara Radziszewska, Felipe Sierra, Ronald Kohanski, Miroslaw Mackiewicz, Francesca Macchiarini, Mercy PrabhuDas, Merriline Vedamony, Preethi Chander, Michelle Hamlet and Johanna Dwyer.

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Authors and Affiliations

  1. National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

    Christina H Liu

  2. National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA

    Natalie D Abrams, Danielle M Carrick & Pushpa Tandon

  3. National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA

    Preethi Chander

  4. NIH Office of Dietary Supplements, National Institutes of Health, Bethesda, Maryland, USA

    Johanna Dwyer

  5. National Institute of Nursing Research, National Institutes of Health, Bethesda, Maryland, USA

    Michelle R J Hamlet

  6. National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA

    Francesca Macchiarini

  7. National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA

    Mercy PrabhuDas & Merriline M Vedamony

  8. National Eye Institute, National Institutes of Health, Rockville, Maryland, USA

    Grace L Shen

Authors
  1. Christina H Liu
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  2. Natalie D Abrams
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Correspondence to Christina H Liu.

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The authors declare no competing financial interests.

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Liu, C., Abrams, N., Carrick, D. et al. Biomarkers of chronic inflammation in disease development and prevention: challenges and opportunities. Nat Immunol 18, 1175–1180 (2017). https://doi.org/10.1038/ni.3828

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