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Tumor immunity requires border patrol to fight the enemy within

The infiltration of solid tumors by CD8+ T cells is a favorable prognostic marker. Large-scale transcriptome analysis of tumor-infiltrating T cells from mucosal tumors shows that CD8+ T cells with a CD103+ tissue-resident memory T cell phenotype might be the most desirable.

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Figure 1: Tissue-resident memory T cells in solid tumors.

Debbie Maizels/Springer Nature

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Correspondence to Derk Amsen.

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Amsen, D., Hombrink, P. & van Lier, R. Tumor immunity requires border patrol to fight the enemy within. Nat Immunol 18, 870–872 (2017). https://doi.org/10.1038/ni.3792

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