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IL-1β delivers a sweet deal

Interleukin 1β (IL-1β) is a cytokine associated with inflammation, obesity and metabolic dysregulation. Surprisingly, IL-1β is also required for maintaining steady-state glucose homeostasis by potentiating postprandial insulin secretion.

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Figure 1: IL-1β potentiates postprandial secretion of insulin.

Marina Corral Spence/ Springer Nature

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Correspondence to Mark A Febbraio.

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Hjorth, M., Febbraio, M. IL-1β delivers a sweet deal. Nat Immunol 18, 247–248 (2017). https://doi.org/10.1038/ni.3681

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