Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Linking air pollution to atopic dermatitis

The relationship between atopic dermatitis and air pollution has been long debated but has now been connected via the aryl hydrocarbon receptor and its control of skin innervation and the consequent triggering of an itch-scratch response.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: The relationship between AD and air pollution.

Kim Caesar / Nature Publishing Group

References

  1. Kabashima, K. J. Dermatol. Sci. 70, 3–11 (2013).

    Article  Google Scholar 

  2. Otsuka, A. et al. J. Allergy Clin. Immunol. 133, 139–146 (2014).

    Article  CAS  Google Scholar 

  3. Hidaka, T. et al. Nat. Immunol. 18, 64–73 (2017).

    Article  CAS  Google Scholar 

  4. Wilson, S.R. et al. Cell 155, 285–295 (2013).

    Article  CAS  Google Scholar 

  5. Furue, M. et al. J. Dermatol. Sci. 80, 83–88 (2015).

    Article  CAS  Google Scholar 

  6. Schäfer, M. et al. EMBO Mol. Med. 6, 442–457 (2014).

    Article  Google Scholar 

  7. Elitt, C.M. et al. J. Neurosci. 26, 8578–8587 (2006).

    Article  CAS  Google Scholar 

  8. Julius, D. Annu. Rev. Cell Dev. Biol. 29, 355–384 (2013).

    Article  CAS  Google Scholar 

  9. Murota, H. et al. J. Allergy Clin. Immunol. 130, 671–682 (2012).

    Article  CAS  Google Scholar 

  10. Malin, S.A. et al. J. Neurosci. 26, 8588–8599 (2006).

    Article  CAS  Google Scholar 

  11. Yoshida, N. et al. Mol. Pain 7, 41 (2011).

    Article  CAS  Google Scholar 

  12. Haas, K. et al. J. Invest. Dermatol. http://dx.doi.org/10.1016/j.jid.2016.06.627 (2016).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kenji Kabashima.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Kabashima, K., Otsuka, A. & Nomura, T. Linking air pollution to atopic dermatitis. Nat Immunol 18, 5–6 (2017). https://doi.org/10.1038/ni.3615

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ni.3615

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing