CD1a on Langerhans cells in the epidermis is the lipid receptor for the plant-derived allergen urushiol and self lipids and is a key amplifier of inflammatory responses in urushiol-induced contact dermatitis as well as in psoriasis.
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Amagai, M. Cracking the code of skin inflammation with CD1a. Nat Immunol 17, 1133–1134 (2016). https://doi.org/10.1038/ni.3557
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DOI: https://doi.org/10.1038/ni.3557
