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Eosinophils and mast cells: a lineage apart

Nature Immunology volume 17, pages 609–611 (2016)Cite this article

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Single-cell transcriptome analysis has identified progenitor populations with mast-cell and eosinophil potential that are distinct from the neutrophil-monocyte lineage, segregate early in hematopoietic development and can be discriminated by expression of the transcription factor GATA-1.

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Figure 1: Current and revised models of granulopoiesis.

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Authors and Affiliations

  1. Sandrine Sarrazin is with the Centre d'Immunologie de Marseille-Luminy (CIML), Université Aix-Marseille, UM2, Campus de Luminy, Case 906, Marseille, France, the Institut National de la Santé et de la Recherche Médicale (INSERM), U1104, Marseille, France, and the Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France.,

    Sandrine Sarrazin

  2. Michael H. Sieweke is with the Centre d'Immunologie de Marseille-Luminy (CIML), Université Aix-Marseille, UM2, Campus de Luminy, Case 906, Marseille, France, the Institut National de la Santé et de la Recherche Médicale (INSERM), U1104, Marseille, France, the Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France, and the Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC), Berlin, Germany.,

    Michael H Sieweke

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  1. Sandrine Sarrazin
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  2. Michael H Sieweke
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Correspondence to Michael H Sieweke.

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Sarrazin, S., Sieweke, M. Eosinophils and mast cells: a lineage apart. Nat Immunol 17, 609–611 (2016). https://doi.org/10.1038/ni.3446

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