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ILC development: TCF-1 reporting in

The transcriptional regulator TCF-1 marks rare progenitor cells in adult bone marrow that have lost the potential to develop into the lymphocyte lineage but can give rise to all innate lymphoid cell lineages.

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Figure 1: Pathway of ILC development in adult bone marrow.

References

  1. Yang, Q.L. et al. Nat. Immunol. 16, 1044–1050 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Artis, D. & Spits, H. Nature 517, 293–301 (2015).

    Article  CAS  PubMed  Google Scholar 

  3. Yagi, R. et al. Immunity 40, 378–388 (2014).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Klose, C.S. et al. Cell 157, 340–356 (2014).

    Article  CAS  PubMed  Google Scholar 

  5. Constantinides, M.G., McDonald, B.D., Verhoef, P.A. & Bendelac, A. Nature 508, 397–401 (2014).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Aliahmad, P., de la Torre, B. & Kaye, J. Nat. Immunol. 11, 945–952 (2010).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Seehus, C.R. et al. Nat. Immunol. 16, 599–608 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Yu, X., et al. Elife 3, (2014).

  9. Weber, B.N. et al. Nature 476, 63–68 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Wong, S.H. et al. Nat. Immunol. 13, 229–236 (2012).

    CAS  PubMed  PubMed Central  Google Scholar 

  11. Cherrier, M., Sawa, S. & Eberl, G. J. Exp. Med. 209, 729–740 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Xu, W. et al. Cell Rep 10, 2043–2054 (2015).

    Article  CAS  PubMed  Google Scholar 

Download references

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Correspondence to Jonathan Kaye.

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Kaye, J. ILC development: TCF-1 reporting in. Nat Immunol 16, 1011–1012 (2015). https://doi.org/10.1038/ni.3276

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