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Sirt-ainly Aire

Nature Immunology volume 16, pages 680681 (2015) | Download Citation

Sirtuin-1 (Sirt1), a protein deacetylase known for its multiple cellular functions, including roles in metabolism, stress response and aging, is a post-translational modulator of autoimmune regulator (Aire) in central immunotolerance.

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Author information

Affiliations

  1. Pärt Peterson is at the Molecular Pathology Research Group, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.

    • Pärt Peterson

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Competing interests

The author declares no competing financial interests.

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Correspondence to Pärt Peterson.

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DOI

https://doi.org/10.1038/ni.3195

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