Due to their role in regulating DNA-methylation patterns, the TET proteins, in particular TET2, have emerged as key participants in tumorigenesis. Now the spotlight shifts to TET1 and its role as a tumor suppressor in lymphomagenesis.
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Rasmussen, K., Helin, K. TET1: an epigenetic guardian of lymphomagenesis. Nat Immunol 16, 592–594 (2015). https://doi.org/10.1038/ni.3176
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DOI: https://doi.org/10.1038/ni.3176