Heng, T.S. & Painter, M.W. The Immunological Genome Project: networks of gene expression in immune cells. Nat. Immunol. 9, 1091–1094 (2008).
Diefenbach, A., Colonna, M. & Koyasu, S. Development, differentiation, and diversity of innate lymphoid cells. Immunity 41, 354–365 (2014).
McKenzie, A.N., Spits, H. & Eberl, G. Innate lymphoid cells in inflammation and immunity. Immunity 41, 366–374 (2014).
Klose, C.S. et al. Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages. Cell 157, 340–356 (2014).
Sawa, S. et al. Lineage relationship analysis of RORgammat+ innate lymphoid cells. Science 330, 665–669 (2010).
Lee, J.S. et al. AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nat. Immunol. 13, 144–151 (2011).
Klose, C.S. et al. A T-bet gradient controls the fate and function of CCR6-Rorγt+ innate lymphoid cells. Nature 494, 262–265 (2013).
Sciumé, G. et al. Distinct requirements for T-bet in gut innate lymphoid cells. J. Exp. Med. 209, 2331–2338 (2012).
Rankin, L.C. et al. The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway. Nat. Immunol. 14, 389–395 (2013).
Buonocore, S. et al. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature 464, 1371–1375 (2010).
Constantinides, M.G., McDonald, B.D., Verhoef, P.A. & Bendelac, A. A committed precursor to innate lymphoid cells. Nature 508, 397–401 (2014).
Yu, J., Freud, A.G. & Caligiuri, M.A. Location and cellular stages of natural killer cell development. Trends Immunol. 34, 573–582 (2013).
Gordon, S.M. et al. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity 36, 55–67 (2012).
Reynders, A. et al. Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt– lymphoid cells. EMBO J. 30, 2934–2947 (2011).
Gasteiger, G., Hemmers, S., Bos, B.D., Sun, J.C. & Rudensky, A.Y. IL-2-dependent adaptive control of NK cell homeostasis. J. Exp. Med. 210, 1179–1187 (2013).
Fuchs, A. et al. Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-γ-producing cells. Immunity 38, 769–781 (2013).
Turner, J.E. et al. IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J. Exp. Med. 210, 2951–2965 (2013).
Mjösberg, J. et al. The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. Immunity 37, 649–659 (2012).
Yagi, R. et al. The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells. Immunity 40, 378–388 (2014).
Evans, R.M. & Mangelsdorf, D.J. Nuclear receptors, RXR, and the Big Bang. Cell 157, 255–266 (2014).
Spencer, S.P. et al. Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity. Science 343, 432–437 (2014).
Molofsky, A.B. et al. Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages. J. Exp. Med. 210, 535–549 (2013).
Mohebiany, A.N., Harroch, S. & Bouyain, S. in Cell Adhesion Molecules: Implications in Neurological Diseases, Advances in Neurobiology Vol. 8 (eds. Berezin, V. & Walmod, P.S.) Chapter 8 (Springer Science+Business Media, 2014).
Cella, M. et al. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 457, 722–725 (2009).
Mortha, A. et al. Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal tolerance. Science 343, 1249288 (2014).
Levitt, L.J. et al. Production of granulocyte/macrophage-colony stimulating factor by human natural killer cells. Modulation by the p75 subunit of the interleukin 2 and by the CD2 receptor. J. Clin. Invest. 88, 67–75 (1991).
van de Pavert, S.A. et al. Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity. Nature 508, 123–127 (2014).
Kiss, E.A. et al. Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles. Science 334, 1561–1565 (2011).
Gascoyne, D.M. et al. The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat. Immunol. 10, 1118–1124 (2009).
Kamizono, S. et al. Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo. J. Exp. Med. 206, 2977–2986 (2009).
Seillet, C. et al. Nfil3 is required for the development of all innate lymphoid cell subsets. J. Exp. Med. 211, 1733–1740 (2014).
Geiger, T.L. et al. Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens. J. Exp. Med. 211, 1723–1731 (2014).
Muller, P.A. et al. Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility. Cell 158, 300–313 (2014).
Bando, J.K., Liang, H.E. & Locksley, R.M. Identification and distribution of developing innate lymphoid cells in the fetal mouse intestine. Nat. Immunol. http://www.nature.com/ni/journal/vaop/ncurrent/full/ni.3057.html (2014).
Veiga-Fernandes, H. et al. Tyrosine receptor RET is a key regulator of Peyer's patch organogenesis. Nature 446, 547–551 (2007).
Ramirez, K. et al. Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1. Immunity 36, 921–932 (2012).
Carpenter, S., Ricci, E.P., Mercier, B.C., Moore, M.J. & Fitzgerald, K.A. Post-transcriptional regulation of gene expression in innate immunity. Nat. Rev. Immunol. 14, 361–376 (2014).
Kumanogoh, A. & Kikutani, H. Immunological functions of the neuropillins and plexins as receptors for semaphorins. Nat. Rev. Immunol. 13, 802–814 (2013).
Yadav, M. et al. Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo. J. Exp. Med. 209, 1713–1722 (2012).
Weiss, J.M. et al. Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. J. Exp. Med. 209, 1723–1742 (2012).
Shen, W. et al. Adaptive immunity to murine skin commensals. Proc. Natl. Acad. Sci. USA 111, E2977–E2986 (2014).
Daussy, C. et al. T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow. J. Exp. Med. 211, 563–577 (2014).
Sojka, D.K. et al. Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells. Elife 3, e01659 (2014).
Ye, S.K. et al. Induction of germline transcription in the Tcrγ locus by Stat5: implications for accessibility control by the IL-7 receptor. Immunity 11, 213–223 (1999).
Zhao, H., Nguyen, H. & Kang, J. Interleukin 15 controls the generation of restricted T cell receptor repertoire of intraepithelial lymphocytes. Nat. Immunol. 6, 1263–1271 (2005).
Allan, D.S. et al. An in vitro model of innate lymphoid cell function and differentiation. Mucosal Immunol. http://www.nature.com/mi/journal/vaop/ncurrent/full/mi201471a.html (2014).
Yu, X. et al. The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell progenitor. Elife 10, e04406 (2014).
Satoh-Takayama, N. et al. The chemokine receptor CXCR6 controls the functional topograophy of interluekin-22 producing intestinal innate lymphoid cells. Immunity 41, 776–788 (2014).
Bezman, N.A. et al. ImmGen report: molecular definition of natural killer cell identity and activation. Nat. Immunol. 13, 1000–1009 (2012).
Peng, H. et al. Liver-resident NK cells confer adaptive immunity in skin-contact inflammation. J. Clin. Invest. 123, 1444–1456 (2013).
Reich, M. et al. GenePattern 2.0. Nat. Genet. 38, 500–501 (2006).