News & Views | Published:

Breaking barriers: a GPCR triggers immunity in nematodes

Nature Immunology volume 15, pages 826828 (2014) | Download Citation

Subjects

A ligand and G protein–coupled receptor activate antimicrobial gene expression in the Caenorhabditis elegans epidermis, in response to wounding and to infection with a fungal pathogen.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    & Nat. Rev. Immunol. 12, 503–516 (2012).

  2. 2.

    & Nat. Rev. Mol. Cell Biol. 14, 249–262 (2013).

  3. 3.

    et al. Nat. Immunol. 15, 833–838 (2014).

  4. 4.

    & Curr. Opin. Immunol. 24, 3–9 (2012).

  5. 5.

    & Curr. Biol. 21, 1960–1967 (2011).

  6. 6.

    et al. Cell Host Microbe 5, 341–352 (2009).

  7. 7.

    et al. J. Neurosci. 31, 16603–16610 (2011).

  8. 8.

    et al. Cell. Mol. Life Sci. 70, 4307–4321 (2013).

  9. 9.

    Trends Immunol. 35, 345–351 (2014).

  10. 10.

    & Cell Host Microbe 11, 320–322 (2012).

  11. 11.

    & Virulence (6 May 2014).

  12. 12.

    & Mediators Inflamm. 2010, 672395 (2010).

  13. 13.

    , & Mol. Cell 54, 297–308 (2014).

Download references

Author information

Affiliations

  1. Robert J. Luallen and Emily R. Troemel are in the Division of Biological Sciences, Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California, USA.

    • Robert J Luallen
    •  & Emily R Troemel

Authors

  1. Search for Robert J Luallen in:

  2. Search for Emily R Troemel in:

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Emily R Troemel.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/ni.2963

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing