AP4, a transcription factor induced by the functionally related transcription factor c-Myc, maintains the cellular metabolic program for the sustained activation and population expansion of CD8+ T cells after the dynamic loss of c-Myc expression.
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Karmaus, P., Chi, H. c-Myc and AP4: a relay team for metabolic reprogramming of CD8+ T cells. Nat Immunol 15, 828–829 (2014). https://doi.org/10.1038/ni.2962
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DOI: https://doi.org/10.1038/ni.2962