The receptor CD96 inhibits cytokine production by natural killer cells in mice and antagonizes activation mediated by the receptor CD226.
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References
Wang, P.L. et al. J. Immunol. 148, 2600–2608 (1992).
Fuchs, A. et al. J. Immunol. 172, 3994–3998 (2004).
Chan, C.J. et al. Nat. Immunol. 15, 431–438 (2014).
Maier, M.K. et al. Eur. J. Immunol. 37, 2214–2225 (2007).
Shibuya, K. et al. Immunity 11, 615–623 (1999).
Shibuya, K. et al. J. Exp. Med. 198, 1829–1839 (2003).
Joller, N. et al. J. Immunol. 186, 1338–1342 (2011).
Levin, S.D. et al. Eur. J. Immunol. 41, 902–915 (2011).
Stanietsky, N. et al. Proc. Natl. Acad. Sci. USA 106, 17858–17863 (2009).
Stanietsky, N. et al. Eur. J. Immunol. 43, 2138–2150 (2013).
Oda, T., Ohka, S. & Nomoto, A. Biochem. Biophys. Res. Commun. 319, 1253–1264 (2004).
Yu, X. et al. Nat. Immunol. 10, 48–57 (2009).
Koike, S. et al. EMBO J. 9, 3217–3224 (1990).
Meyer, D. et al. J. Biol. Chem. 284, 2235–2244 (2009).
Seth, S. et al. Biochem. Biophys. Res. Commun. 364, 959–965 (2007).
Gramatzki, M. et al. Exp. Hematol. 26, 1209–1214 (1998).
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Bernhardt, G. TACTILE becomes tangible: CD96 discloses its inhibitory peculiarities. Nat Immunol 15, 406–408 (2014). https://doi.org/10.1038/ni.2855
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DOI: https://doi.org/10.1038/ni.2855
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