Interleukin 17 (IL-17) confers protection against Trypanosoma cruzi. Surprisingly, B cells are the relevant source, producing IL-17 via a unique pathway independent of the transcription factor RORγt, induced by T. cruzi trans-sialidase.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Vaccination with Mycoplasma pneumoniae membrane lipoproteins induces IL-17A driven neutrophilia that mediates Vaccine-Enhanced Disease
npj Vaccines Open Access 29 July 2022
-
Interleukin 17A as a good predictor of the severity of Mycoplasma pneumoniae pneumonia in children
Scientific Reports Open Access 11 October 2017
-
The excretory-secretory products of Echinococcus granulosus protoscoleces directly regulate the differentiation of B10, B17 and Th17 cells
Parasites & Vectors Open Access 21 July 2017
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Katie Vicari
References
Eberl, G. Immunol. Rev. 245, 177–188 (2012).
Weaver, C.T., Elson, C.O., Fouser, L.A. & Kolls, J.K. Annu. Rev. Pathol. 8, 477–512 (2013).
Zhou, L. & Littman, D.R. Curr. Opin. Immunol. 21, 146–152 (2009).
Bermejo, D.A. et al. Nat. Immunol. 14, 514–522 (2013).
Giorgi, M.E. & de Lederkremer, R.M. Carbohydr. Res. 346, 1389–1393 (2011).
Muiá, R.P. et al. Glycobiology 20, 833–842 (2010).
Saunders, A.E. & Johnson, P. Cell Signal. 22, 339–348 (2010).
Clark, M.C. & Baum, L.G. Ann. NY Acad. Sci. 1253, 58–67 (2012).
Yuki, N. & Koga, M. Curr. Opin. Neurol. 19, 451–457 (2006).
Fritz, J.H. et al. Nature 481, 199–203 (2012).
Pillai, S., Netravali, I.A., Cariappa, A. & Mattoo, H. Annu. Rev. Immunol. 30, 357–392 (2012).
Chan, A.C. Mol. Immunol. 48, 1344–1347 (2011).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
León, B., Lund, F. IL-17-producing B cells combat parasites. Nat Immunol 14, 419–421 (2013). https://doi.org/10.1038/ni.2593
Published:
Issue Date:
DOI: https://doi.org/10.1038/ni.2593
This article is cited by
-
Vaccination with Mycoplasma pneumoniae membrane lipoproteins induces IL-17A driven neutrophilia that mediates Vaccine-Enhanced Disease
npj Vaccines (2022)
-
The excretory-secretory products of Echinococcus granulosus protoscoleces directly regulate the differentiation of B10, B17 and Th17 cells
Parasites & Vectors (2017)
-
Interleukin 17A as a good predictor of the severity of Mycoplasma pneumoniae pneumonia in children
Scientific Reports (2017)
-
Identification of the salmonid IL-17A/F1a/b, IL-17A/F2b, IL-17A/F3 and IL-17N genes and analysis of their expression following in vitro stimulation and infection
Immunogenetics (2015)
