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When metabolism met immunology

Nature Immunology volume 14, pages 421422 (2013) | Download Citation

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Obesity induces metabolic stress and is associated with inflammation. A cellular pathway now links SIRT2, a deacetylase involved in metabolic processes, to cytoskeleton remodelling and activation of the NLRP3 inflammasome.

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Author information

Affiliations

  1. Marc Y. Donath is in the Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland.

    • Marc Y Donath

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  1. Search for Marc Y Donath in:

Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Marc Y Donath.

About this article

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DOI

https://doi.org/10.1038/ni.2591

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