Becoming covered in platelets rescues complement-opsonized blood-borne bacteria from rapid clearance by macrophages and redirects them to dendritic cells. Although this allows priming of T cells and the generation of immune memory, bacteria can exploit this route as a beachhead and disseminate throughout host tissues.
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Marina Corral
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Jung, S. A rescue gone wrong. Nat Immunol 12, 1137–1138 (2011). https://doi.org/10.1038/ni.2161
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DOI: https://doi.org/10.1038/ni.2161
