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ASCertaining cytoskeletal rearrangements in antigen presentation and migration

Nature Immunology volume 12, pages 923–925 (2011)Cite this article

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An Erratum to this article was published on 19 July 2013

This article has been updated

ASC has emerged as an adaptor for inflammasome sensors in cells of the innate immune response. New inflammasome-independent roles have been identified for ASC in the control of adaptive immunity; these include the post-transcriptional regulation of cytoskeletal rearrangements.

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Figure 1: Inflammasome-dependent and inflammasome-independent functions of ASC in cells of the immune response.

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  • 01 June 2012

    The Nature Immunology article to which this News & Views refers has an associated addendum. We want to inform readers that some of the comments made in this News & Views, although made in good faith on the basis of the article's conclusions, may no longer be valid.

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Authors and Affiliations

  1. Ioannis Karakasiliotis and Dimitris L. Kontoyiannis are with the Institute of Immunology, Biomedical Sciences Research Center 'Alexander Fleming', Vari, Greece.,

    Ioannis Karakasiliotis & Dimitris L Kontoyiannis

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  1. Ioannis Karakasiliotis
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  2. Dimitris L Kontoyiannis
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Correspondence to Dimitris L Kontoyiannis.

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Karakasiliotis, I., Kontoyiannis, D. ASCertaining cytoskeletal rearrangements in antigen presentation and migration. Nat Immunol 12, 923–925 (2011). https://doi.org/10.1038/ni.2114

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